Fatigue

tiredness not relieved by rest

Fatigue can be mental: headaches, loss of concentration, depression, difficulty sleeping or sleeping too much. fatigue can be physical: pain, weakness, muscle aches

When does fatigue start and how long does it last?

On average, fatigue begins 1 month after starting treatment and often lasts for four months.
The severity most often experienced is grade 1 or 2

How serious is fatigue?

How likely is it that I will experience fatigue?

Lorlatinib: 27% of people will experience fatigue. Alectinib: 25% of people will experience fatigue. Crizotinib: 29% of people will experience fatigue.

Prevention Strategies

bed with alarm clock
  • Aim for 7-8h of sleep a night.

    Go to bed and wake up at the same time each day (even on weekends).

    Take short naps as needed (30 min).

    Create a calming bedtime routine.

    Doctor may prescribe sleeping medications.

    Why: having a regular bedtime routine maintains the timing of the body's internal clock and can help you fall asleep and wake up more easily.

black woman speed walking
  • Try activities like walking, riding a bike, swimming, and yoga.

    Start slow and build up the difficulty gradually.

    Why: Exercise can build stamina which can reduce fatigue if it sets in.

magnifying glass
  • Your doctor will monitor for other causes including:

    • Anaemia (low red blood cell number): monitored with blood tests.

    • Neutropenia (low white blood cell number): monitored with blood tests.

    • Depression or anxiety: monitored by doctor.

    Why: catching the underlying cause of fatigue can prevent it from worsening.

Management Strategies

battery with two bars left and lightning bolt in front.
  • Save energy for the most important activities.

    Keep track of when you feel the most energy and plan to do activities then.

    Drink enough water and eat healthy foods to maintain energy.

holding hands
  • Establish a support system who can help with activities like shopping, housework, and cooking.

    Knowing you have people who are there to help can boost energy.

three z's to represent sleep
  • Pay attention to when you are feel the most fatigued and plan to rest at those times.

    Many people experience fatigue in the mid afternoon.

    Limit naps to no longer than an hour.

Emergent Symptoms

If you are unsure, it is always safer to seek medical care.
Tell emergency staff you are on an ALK inhibitor for lung cancer.

phone

Call a Healthcare Provider

Call 811 for general health advice from a registered nurse OR call your care team

  • New or worse tiredness

  • Tiredness that does not get better with rest

  • Dizziness but you do not pass out

  • Weakness that does not go away

  • Tiredness with fever or signs of infection

  • Tiredness with poor appetite or weight loss

  • New tiredness after starting or changing your ALK medicine

ambulance

Visit an Emergency Room

Call 911 or drive to your closest emergency room

  • Sudden, severe weakness

  • Passing out

  • New confusion

  • Chest pain

  • Trouble breathing

  • Sudden trouble talking, seeing, or moving one side

  • Very hard to stay awake

  • Very fast, very slow, or uneven heartbeat

Download Fatigue Info Sheet
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